Southeastern Association of Blood Bankers - SEABB - AABB Weekly Report

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Two teams of researchers may have found one reason why patients who receive blood transfusions sometimes fare worse than those who don't.

Blood stored in blood banks may lose a naturally occurring chemical that improves blood flow, a finding that is spurring research to determine if restoring the chemical could solve the problem.

Concerns that transfusions may be harmful to some patients have been around at least since 1999, when a study published in the New England Journal of Medicine found that patients treated with an aggressive transfusion regimen did at least as well as those who were treated with a more conservative regimen. For younger patients and those who were less acutely ill, more aggressive use of transfusions increased the risk of death.

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AABB Weekly Report - 2/1/08

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